OXEDRINE


SMILES CNCC(O)c1ccc(O)cc1
InChIKey YRCWQPVGYLYSOX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 167.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Ligand site mutations α1A α1B α2A β2

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Human Adrenoceptors A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.2 4.2 4.2 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.38 8.38 8.38 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NMU2 NMUR2 Human Neuromedin U A pEC50 5.18 5.18 5.18 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.85 5.85 5.85 ChEMBL
NMU2 NMUR2 Human Neuromedin U A pEC50 8.29 8.29 8.29 Drug Central