GPCRdb

CHEMBL362543

Agent/drug
Bioactivity

CHEMBL362543

SMILES	O=C(O)c1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1
InChIKey	RRDVGFBNUNMAKI-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	420.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pKi	7.16	8.70	9.52	ChEMBL
TP	TA2R	Human	Prostanoid	A	pKi	7.00	7.00	7.00	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pIC50	8.20	8.32	8.45	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL362543

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.