GPCRdb

CHEMBL363730

Agent/drug
Bioactivity

CHEMBL363730

SMILES	CC1CN(/C(=N/c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2)NC2CCCCC2)CC(C)N1
InChIKey	QDDPPGFVMRPNTQ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	3
Rotatable bonds	6
Molecular weight (Da)	529.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₃	MC3R	Human	Melanocortin	A	pKi	5.41	5.41	5.41	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	6.23	6.23	6.23	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pKi	7.96	7.96	7.96	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₄	MC4R	Human	Melanocortin	A	pEC50	5.40	5.40	5.40	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pIC50	7.10	7.10	7.10	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL363730

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.