CHEMBL364560


SMILES COc1ccc(CC(=O)NCC2(N3CCN(C(=O)[C@@H](Cc4ccc(Cl)cc4Cl)NC(=O)CCN)CC3)CCCCC2)cc1
InChIKey SDXNKLFMLKIOBP-MUUNZHRXSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 12
Molecular weight (Da) 631.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.24 5.24 5.24 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.27 6.27 6.27 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.96 5.96 5.96 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.38 8.44 8.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database