CHEMBL3409035


SMILES NC(=O)[C@@H]1Cc2ccccc2CN1C(=O)CCCCN1CCN(c2ccccc2-c2ccccc2)CC1
InChIKey IJROQVYQUCVUHW-LJAQVGFWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 496.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.03 7.72 8.22 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.23 6.23 6.23 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.18 7.18 7.18 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database