CHEMBL365278


SMILES O=C(N[C@H](Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ccccc2CNCCc2ccccc2F)CC1)[C@H]1Cc2ccccc2CN1
InChIKey TXSUTEHZKIBGJG-VSJLXWSYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 653.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 7.38 7.38 7.38 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.58 6.58 6.58 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.64 5.64 5.64 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.57 7.57 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 6.04 6.04 6.04 ChEMBL