CHEMBL365405


SMILES CN1CCC(n2ncc3ccc(NC(=O)c4ccc(F)cc4)cc32)CC1
InChIKey UFYXGIYTVOXGRK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.39 8.39 8.39 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.62 5.62 5.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.51 6.51 6.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database