CHEMBL365499


SMILES N#Cc1cccc(-n2nnc(-c3ccccn3)n2)c1
InChIKey OGIBYDWBTRKAOL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 248.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.72 6.79 6.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 7.14 7.14 7.14 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.14 7.15 7.16 ChEMBL