CHEMBL349850


SMILES CN(C)Cc1ccccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2)CC1
InChIKey VJWZUOKQCXSJRH-FQLXRVMXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 559.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Human Melanocortin A pKi 5.85 5.85 5.85 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.16 5.16 5.16 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.22 7.22 7.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Human Melanocortin A pEC50 5.75 5.75 5.75 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 8.15 8.15 8.15 ChEMBL