CHEMBL3659220


SMILES O=C(c1cccc(F)c1-c1ncccn1)N1C2CCC1C(COc1ccccn1)C2
InChIKey MVONBPRQLZYVPK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 6.46 6.46 6.46 ChEMBL
OX2 OX2R Human Orexin A pKi 5.64 5.64 5.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database