CHEMBL352375


SMILES CC(C1=C(CCN(C(C)C)C(C)C)Cc2ccccc21)c1ccccn1
InChIKey HBRHULDGKNIFGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 348.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 4.93 5.29 5.66 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.26 5.71 6.13 ChEMBL
H1 HRH1 Human Histamine A pKi 5.61 6.13 6.66 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 4.68 5.24 5.65 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.24 7.07 7.6 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.23 5.72 6.13 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database