GPCRdb

CHEMBL1188090

Agent/drug
Bioactivity

CHEMBL1188090

SMILES	CCCN(CCc1ccccc1)CCc1cccc(O)c1
InChIKey	QUZUPTMNMJTYGL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	8
Molecular weight (Da)	283.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	5.43	5.43	5.43	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	8.09	8.09	8.09	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	6.23	6.23	6.23	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.19	7.19	7.19	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	7.66	7.66	7.66	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

κ	OPRK	Guinea pig	Opioid	A	pIC50	7.24	7.24	7.24	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	7.31	7.31	7.31	ChEMBL
D₁	DRD1	Rat	Dopamine	A	pIC50	4.03	4.03	4.03	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pIC50	6.12	6.12	6.12	ChEMBL
D₂	DRD2	Human	Dopamine	A	pEC50	7.41	7.41	7.41	ChEMBL
D₃	DRD3	Human	Dopamine	A	pEC50	8.27	8.27	8.27	ChEMBL

Showing 1 to 6 of 6 entries

CHEMBL1188090

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.