CHEMBL3597632


SMILES Cc1c(CCCC(=O)O)c2c(F)ccc(C#Cc3ccc(OCCCCc4c(F)cc(F)c(F)c4F)cc3)c2n1CCCC(=O)O
InChIKey HOXJOAWSVADHMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 14
Molecular weight (Da) 641.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CysLT2 CLTR2 Human Leukotriene A pIC50 7.89 7.89 7.89 ChEMBL
CysLT1 CLTR1 Guinea pig Leukotriene A pIC50 8.37 8.37 8.37 ChEMBL
CysLT1 CLTR1 Human Leukotriene A pIC50 8.13 8.13 8.13 ChEMBL