CHEMBL3676877


SMILES O=C(N[C@H]1CC[C@H](CCN2CCC(c3coc4ccccc34)CC2)CC1)C(O)C(F)(F)F
InChIKey NHQVWADCZMCLLL-MYKGNVCDSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 452.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 7.33 7.33 7.33 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database