GPCRdb

OLOPATADINE

Agent/drug
Bioactivity

OLOPATADINE

SMILES	CN(C)CC/C=C1/c2ccccc2COc2ccc(CC(=O)O)cc21
InChIKey	JBIMVDZLSHOPLA-LSCVHKIXSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	5
Molecular weight (Da)	337.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem PubChem DrugBank PubChem GPCRdb
Ligand site mutations	H₁

No bioactivity data available.

OLOPATADINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 0

Phase II 0

Phase III 1

Approved Yes

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem PubChem DrugBank PubChem GPCRdb
Ligand site mutations	H₁

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

HRH1	H₁ receptor	Histamine receptors	Aminergic receptors	Class A	Allergic conjunctivitis	9A60.02		0.589	4	Yes
HRH1	H₁ receptor	Histamine receptors	Aminergic receptors	Class A	Allergic rhinitis due to other seasonal allergens	CA08.01		0.610	4	Yes
HRH1	H₁ receptor	Histamine receptors	Aminergic receptors	Class A	Allergic rhinitis, unspecified	CA08.0Z		0.616	4	Yes
HRH1	H₁ receptor	Histamine receptors	Aminergic receptors	Class A	Nasal congestion	MD11.9		0.607	4	Yes
HRH1	H₁ receptor	Histamine receptors	Aminergic receptors	Class A	Other allergic rhinitis	CA08.03		0.602	3	Yes

Showing 1 to 5 of 5 entries