CHEMBL3616850


SMILES N[C@@]1(C(=O)O)C[C@@H](Sc2nnc(C(F)F)[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey HQTAUDRHEUIJTC-JVIRPSFQSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 5
Molecular weight (Da) 334.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.2 7.2 7.2 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.02 7.02 7.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 6.34 6.57 6.81 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 7.11 7.11 7.11 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.27 7.6 7.93 ChEMBL