CHEMBL3616858


SMILES Nc1nnc(S[C@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@H]23)[nH]1
InChIKey PZICKINIOPPAGP-CWOZVJDESA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 4
Molecular weight (Da) 299.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.16 7.16 7.16 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.56 7.56 7.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.41 5.41 5.41 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 6.95 6.95 6.95 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.7 7.95 8.19 ChEMBL