CHEMBL3633656


SMILES COc1ccc(-c2[nH]c3ccccc3c2C(=O)CN(C)CC(=O)N2CCOCC2)cc1
InChIKey LRHFIHBNRRLFSM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPRC6 GPC6A Mouse C Orphans C pIC50 5.03 5.03 5.03 ChEMBL
CaS CASR Rat Calcium-sensing C pIC50 4.25 4.25 4.25 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 4.38 4.38 4.38 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pIC50 4.24 4.81 5.38 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 4.29 4.29 4.29 ChEMBL