CHEMBL3634007


SMILES COc1ccc(C(C)NC(=O)COc2cc(C(F)(F)F)c3c(-c4ccccc4)nn(C)c3n2)cc1
InChIKey GUDQJFKBBOAOIC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.54 7.54 7.54 ChEMBL
OX1 OX1R Human Orexin A pKd 7.5 7.5 7.5 ChEMBL
OX2 OX2R Human Orexin A pKi 8.7 8.7 8.7 ChEMBL
OX2 OX2R Human Orexin A pKd 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database