CHEMBL3634025


SMILES Cc1ccc([C@H](C)NC(=O)COc2cc(C)c3c(-c4cnccn4)nn(C)c3n2)cc1
InChIKey OHTWQRAVWUWAEJ-INIZCTEOSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 416.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.28 7.28 7.28 ChEMBL
OX1 OX1R Human Orexin A pKd 7.7 7.7 7.7 ChEMBL
OX2 OX2R Human Orexin A pKi 7.82 7.82 7.82 ChEMBL
OX2 OX2R Human Orexin A pKd 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database