CHEMBL369310
| SMILES | Cc1nc(C#Cc2ccc(-c3cccnc3)nc2)cs1 |
| InChIKey | PTKUANYKLGZFAX-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 1 |
| Molecular weight (Da) | 277.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pKi | 7.95 | 8.32 | 8.7 | ChEMBL |
| mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pKi | 8.25 | 8.29 | 8.33 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| mGlu5 | GRM5 | Rat | Metabotropic glutamate | C | pIC50 | 8.28 | 8.28 | 8.28 | ChEMBL |
| mGlu5 | GRM5 | Human | Metabotropic glutamate | C | pIC50 | 8.21 | 8.46 | 8.7 | ChEMBL |