CHEMBL370029


SMILES NC(=O)c1ccc2c(c1O)[C@]13CCN(CC4CCC4)[C@H](C2)[C@]1(O)CCC(=O)C3
InChIKey SIIKUSQIIPEOEA-ZPMCFJSWSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.38 8.38 8.38 ChEMBL
κ OPRK Human Opioid A pKi 9.57 9.57 9.57 ChEMBL
μ OPRM Human Opioid A pKi 9.8 9.85 9.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pEC50 9.0 9.0 9.0 ChEMBL
μ OPRM Human Opioid A pIC50 8.66 8.66 8.66 ChEMBL