GPCRdb

CHEMBL370758

Agent/drug
Bioactivity

CHEMBL370758

SMILES	O=C1[C@@H]2CCCN2C(=O)CN1CN1CCN(c2cccc3ccccc23)CC1
InChIKey	CTZWGZSINBFHFD-FQEVSTJZSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	3
Molecular weight (Da)	378.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	8.39	8.39	8.39	ChEMBL
5-HT₇	5HT7R	Rat	5-Hydroxytryptamine	A	pKi	7.00	7.00	7.00	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	6.72	6.72	6.72	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	6.82	6.82	6.82	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL370758

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.