CHEMBL366388


SMILES O=C(CCCN1CCN(C2CCCc3ccccc32)CC1)c1ccc(F)cc1
InChIKey JGHINESLHSSDOZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 7.38 7.38 7.38 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 7.75 7.75 7.75 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 6.0 6.0 6.0 ChEMBL
D2 DRD2 Bovine Dopamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.77 7.77 7.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.68 6.68 6.68 ChEMBL