CHEMBL372020


SMILES CCCN(CCC)[C@H]1CCn2c(C#N)ccc2C1
InChIKey VQEFMIATWHWTNX-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 245.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.01 6.21 7.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.85 7.71 8.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.19 6.02 6.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pEC50 6.89 7.13 7.38 ChEMBL
D3 DRD3 Human Dopamine A pEC50 8.62 8.62 8.62 ChEMBL