CHEMBL3669506


SMILES O=C1N(Cc2ncoc2-c2ccccc2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey QVFUJAFYBZRTBG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.65 6.65 6.65 ChEMBL
OX1 OX1R Human Orexin A pKd 6.37 6.37 6.37 ChEMBL
OX2 OX2R Human Orexin A pKd 7.44 7.44 7.44 ChEMBL
OX2 OX2R Human Orexin A pKi 8.1 8.1 8.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database