CHEMBL3669571


SMILES O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1cc3nccnc3cn1)CC2
InChIKey AIDAWRFKCJZKLP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.78 5.78 5.78 ChEMBL
OX1 OX1R Human Orexin A pKi 6.18 6.18 6.18 ChEMBL
OX2 OX2R Human Orexin A pKi 7.09 7.09 7.09 ChEMBL
OX2 OX2R Human Orexin A pKd 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database