CHEMBL3742426


SMILES CCCN(CCN1CCN(c2ccc3cc[nH]c3c2Cl)CC1)[C@H]1CCc2nc(N)sc2C1
InChIKey IQOHRYVJGPXDMK-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 472.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.94 8.94 8.94 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.79 7.79 7.79 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 8.85 8.85 8.85 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.49 8.49 8.49 ChEMBL