CHEMBL376092


SMILES COc1ccccc1C1CCN(CNC(=O)c2cccc(C)c2)CC1
InChIKey LAFUMJMKVVCEGP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 338.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.57 7.57 7.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 6.69 6.69 6.69 ChEMBL