CHEMBL3681393


SMILES O=C(N[C@H]1CC[C@H](Cn2cc(Cl)c(CO)n2)CC1)c1cc(C(F)(F)F)ccc1Cl
InChIKey MRZCTSJNLTVOQB-AULYBMBSSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 449.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CRF2 CRFR2 Human Corticotropin-releasing factor B1 pIC50 5.32 5.32 5.32 ChEMBL
CRF1 CRFR1 Human Corticotropin-releasing factor B1 pIC50 7.02 7.02 7.02 ChEMBL