GPCRdb

CHEMBL375439

Agent/drug
Bioactivity

CHEMBL375439

SMILES	CCc1ccccc1-n1cnc2c(sc3nccc(N(C)C)c32)c1=O
InChIKey	UTRYCWQCSOJNAJ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	3
Molecular weight (Da)	350.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₁	GRM1	Rat	Metabotropic glutamate	C	pKi	6.85	6.85	6.85	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₁	GRM1	Rat	Metabotropic glutamate	C	pIC50	6.60	6.60	6.60	ChEMBL
mGlu₁	GRM1	Human	Metabotropic glutamate	C	pIC50	6.60	6.60	6.60	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL375439

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.