GPCRdb

CHEMBL375504

Agent/drug
Bioactivity

CHEMBL375504

SMILES	Oc1ccc2c(c1)[C@]13CCN(CC4CCC4)[C@H](C2)[C@@H]1Cc1c([nH]c2ccccc12)C3
InChIKey	OBRHLKNIVAKGEN-HUROMRQRSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	2
Molecular weight (Da)	398.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	9.77	9.77	9.77	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	9.00	9.00	9.00	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	8.41	8.41	8.41	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pIC50	9.22	9.22	9.22	ChEMBL
δ	OPRD	Human	Opioid	A	pEC50	9.10	9.10	9.10	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	6.72	6.72	6.72	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	6.96	6.96	6.96	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL375504

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.