GPCRdb

CHEMBL375559

Agent/drug
Bioactivity

CHEMBL375559

SMILES	CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N1C[C@H](OCc2ccc3ccccc3c2)C[C@@H]1C(=O)NCCN=C(N)N
InChIKey	VZGJDZXPTNTGFA-AOJHZZQJSA-N

Chemical Properties

Hydrogen bond acceptors	7
Hydrogen bond donors	6
Rotatable bonds	15
Molecular weight (Da)	707.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pKi	5.69	5.69	5.69	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pKi	6.30	6.30	6.30	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	6.25	6.25	6.25	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pEC50	5.87	5.87	5.87	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pEC50	5.91	5.91	5.91	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pEC50	6.59	6.59	6.59	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL375559

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.