CHEMBL377779


SMILES CC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N1C[C@H](OCc2ccc3ccccc3c2)C[C@@H]1C(=O)NCCN=C(N)N
InChIKey ZQUWNPZLQBVXOY-GOGZTAQTSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 6
Rotatable bonds 16
Molecular weight (Da) 672.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 6.05 6.05 6.05 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.83 5.83 5.83 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 6.48 6.48 6.48 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.25 6.25 6.25 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 6.74 6.74 6.74 ChEMBL