GPCRdb

CHEMBL3771309

Agent/drug
Bioactivity

CHEMBL3771309

SMILES	CC1(c2ccc(F)cc2)NC(=O)N(CC(O)CN2CCN(c3cccc(Cl)c3Cl)CC2)C1=O
InChIKey	LIBJRLLLOUMXMX-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	2
Rotatable bonds	6
Molecular weight (Da)	494.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	7.23	7.23	7.23	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	7.77	7.77	7.77	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.52	6.52	6.52	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pIC50	5.86	5.86	5.86	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL3771309

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.