CHEMBL3785854


SMILES Oc1ccc2c(c1)[C@]13CCN(CC4CC4)[C@@H](C2)[C@]1(O)Cc1c([nH]c2ccccc12)C3
InChIKey KPFJYRMZTKXKJH-KPRFIHOGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 2
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 10.02 10.02 10.02 ChEMBL
κ OPRK Human Opioid A pKi 8.53 8.53 8.53 ChEMBL
μ OPRM Human Opioid A pKi 7.61 7.61 7.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.85 8.85 8.85 ChEMBL
κ OPRK Human Opioid A pEC50 8.43 8.43 8.43 ChEMBL