GPCRdb

CHEMBL378376

Agent/drug
Bioactivity

CHEMBL378376

SMILES	O=C(O)c1ccc(CCCN2C(=O)CC[C@@H]2CC[C@@H](O)Cc2cccc(C(F)(F)F)c2)s1
InChIKey	JYZXGURJKNAFPT-ZWKOTPCHSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	10
Molecular weight (Da)	469.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₄	PE2R4	Human	Prostanoid	A	pKi	8.70	8.70	8.70	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₂	PE2R2	Rat	Prostanoid	A	pIC50	6.32	6.32	6.32	ChEMBL
EP₄	PE2R4	Rat	Prostanoid	A	pIC50	8.22	8.22	8.22	ChEMBL
EP₄	PE2R4	Rat	Prostanoid	A	pEC50	9.30	9.30	9.30	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pIC50	8.70	8.70	8.70	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL378376

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.