CHEMBL379627


SMILES N=C(N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2c[nH]cn2)NC(=O)CCCCCNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O
InChIKey NKDXCOMNRCSRHU-MLMSKLGMSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 10
Rotatable bonds 10
Molecular weight (Da) 739.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pKi 6.17 6.17 6.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 5.88 5.88 5.88 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 5.51 5.51 5.51 ChEMBL