GPCRdb

CHEMBL3786970

Agent/drug
Bioactivity

CHEMBL3786970

SMILES	O=C1C[C@]23CCN(CC4CC4)[C@H](Cc4ccc(O)cc42)[C@]3(O)C/C1=C\c1ccccc1
InChIKey	IGVCBUFJKDIFNJ-ZKAOPGHISA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	3
Molecular weight (Da)	415.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	8.56	8.56	8.56	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	7.41	7.41	7.41	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	7.66	7.66	7.66	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	7.90	7.90	7.90	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	8.10	8.10	8.10	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL3786970

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.