CHEMBL380365


SMILES CCN(CC)CC(c1ccccc1F)N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)CC2NCCc3ccccc32)CC1
InChIKey NSFFFSYEDFVOOT-QVGGVDQBSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 633.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.52 5.52 5.52 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.04 6.04 6.04 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.38 5.38 5.38 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.98 7.98 7.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database