CHEMBL380540


SMILES CCN(CC)CC(c1ccccc1F)N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3C(C)(C)N2)CC1
InChIKey HEILVIDOVAHKRM-QVGGVDQBSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 11
Molecular weight (Da) 647.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.16 5.16 5.16 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.38 6.38 6.38 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.72 5.72 5.72 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.24 8.24 8.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database