GPCRdb

CHEMBL3797666

Agent/drug
Bioactivity

CHEMBL3797666

SMILES	Cc1ccc(-c2nc(N)c3nn(Cc4ccccc4F)cc3n2)o1
InChIKey	BRLCUIOYTLHZJF-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	323.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A₁	AA1R	Human	Adenosine	A	pKi	6.51	6.51	6.51	ChEMBL
A_2A	AA2AR	Human	Adenosine	A	pKi	7.24	7.24	7.24	ChEMBL
A₃	AA3R	Human	Adenosine	A	pKi	6.30	6.30	6.30	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

A_2B	AA2BR	Human	Adenosine	A	pIC50	6.45	6.45	6.45	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL3797666

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.