CHEMBL380812


SMILES CN1CCN(c2nccc3cc4c(cc23)N(C(=O)c2cnn3ccccc23)CC4)CC1
InChIKey VQJKCIGEXHHGPB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 412.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.9 8.9 8.9 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.5 9.5 9.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database