CHEMBL380858


SMILES CCN(CC)CC(c1ccccc1F)N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)CC2c3ccccc3CN2C)CC1
InChIKey CXNCKVKDTNIURI-XQTVSKJUSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 633.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.07 5.07 5.07 ChEMBL
MC5 MC5R Human Melanocortin A pKi 5.7 5.7 5.7 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.34 5.34 5.34 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.76 7.76 7.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database