CHEMBL3818056


SMILES O=C(CCCN1CCc2ccccc2C1)c1ccc(O)cc1
InChIKey WTLKEIKBWCDFDL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.99 8.0 8.0 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.46 7.46 7.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.07 6.11 6.14 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.84 6.84 6.84 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database