CHEMBL3818398


SMILES O=c1[nH]c2cc(Cl)ccc2n1C1CCN(CCCCc2nc3ccccc3s2)CC1
InChIKey PCHGCRMRRUZREQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 440.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.17 6.17 6.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.79 6.79 6.79 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.67 6.67 6.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database