CHEMBL3818478


SMILES O=C1NCN(c2ccccc2)C12CCN(CCCCc1c[nH]c3ccccc13)CC2
InChIKey IARMAQZFHNEVDV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 402.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 6.56 6.56 6.56 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.69 6.7 6.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.8 8.8 8.81 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.5 7.5 7.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.65 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database