CHEMBL3818989


SMILES O=C(CCCN1CCc2ccccc2C1)c1ccccc1
InChIKey KAHXPONUPROIRS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 279.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.22 6.22 6.22 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.45 6.45 6.45 ChEMBL
H1 HRH1 Human Histamine A pKi 7.17 7.19 7.2 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.15 6.15 6.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.41 8.41 8.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.79 6.79 6.79 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database