dexmedetomidine



dexmedetomidine


SMILES Cc1cccc(c1C)[C@@H](c1c[nH]cn1)C
InChIKey CUHVIMMYOGQXCV-NSHDSACASA-N

Chemical Properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 200.1

Database connections

Structure pdb 7EJA 6K42 6K41 9CBM
Ligand site mutations α2A α2B

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

dexmedetomidine


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Clinical Trials

Phase I 12
Phase II 15
Phase III 30
Approved Yes

Database connections

Structure pdb 7EJA 6K42 6K41 9CBM
Ligand site mutations α2A α2B

Sankey plot

Drug Information

Target Disease Phase
Gene Protein Receptor family Ligand type Class Indication name ICD11 ATC Association score Phase Approved