CHEMBL371300


SMILES C[C@H](N)Cn1ncc2ccc(O)cc21
InChIKey WBYHTZYHAFNBKW-ZETCQYMHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 191.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.1 5.1 5.1 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.33 5.33 5.33 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.64 5.64 5.64 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.09 8.09 8.09 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.52 8.52 8.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pEC50 8.7 8.7 8.7 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pEC50 8.43 8.43 8.43 ChEMBL
α2B ADA2B Human Adrenoceptors A pEC50 5.52 5.52 5.52 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 5.0 5.0 5.0 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pEC50 5.25 5.25 5.25 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 5.58 5.58 5.58 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 5.84 5.84 5.84 ChEMBL